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Structure paper

TitleStructural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 20124-20134, Year 2019
Publish dateJul 10, 2019 (structure data deposition date)
AuthorsLennartz, F. / Smith, C. / Craig, A.G. / Higgins, M.K.
External linksProc. Natl. Acad. Sci. USA / PubMed:31527263
MethodsX-ray diffraction
Resolution2.17 - 3.67 Å
Structure data

PDB-6s8t:
Structure of the ICAM-1-binding PfEMP1 IT4var13 DBLbeta domain
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

PDB-6s8u:
Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1
Method: X-RAY DIFFRACTION / Resolution: 3.67 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • homo sapiens (human)
KeywordsPROTEIN BINDING / PfEMP1 / malaria / cytoadhesion / ICAM-1 / CELL ADHESION

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