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Title | A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 116, Page 19917-19923, Year 2019 |
Publish date | Mar 13, 2019 (structure data deposition date) |
![]() | Song, X. / Yang, L. / Wang, M. / Gu, Y. / Ye, B. / Fan, Z. / Xu, R.M. / Yang, N. |
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Methods | X-ray diffraction |
Resolution | 3.6 Å |
Structure data | ![]() PDB-6jn2: |
Source |
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![]() | TRANSFERASE / hDOT1L / hAF10 / Leucine zipper / heterodimer / tetramerization |