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TitleVersatile Peptide Macrocyclization with Diels-Alder Cycloadditions.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 141, Page 16374-16381, Year 2019
Publish dateJun 27, 2019 (structure data deposition date)
AuthorsMontgomery, J.E. / Donnelly, J.A. / Fanning, S.W. / Speltz, T.E. / Shangguan, X. / Coukos, J.S. / Greene, G.L. / Moellering, R.E.
External linksJ. Am. Chem. Soc. / PubMed:31523967
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-6pit:
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with SRC2 Stapled Peptide 41A and Estradiol
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-EST:
ESTRADIOL / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSCRIPTION / Hormone / Nuclear Receptor / Estrogen / Stapled Peptide

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