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Structure paper

TitleThree-dimensional structure of a high affinity anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain.
Journal, issue, pagesMol. Immunol., Vol. 114, Page 545-552, Year 2019
Publish dateMay 27, 2019 (structure data deposition date)
AuthorsNishiguchi, A. / Numoto, N. / Ito, N. / Azuma, T. / Oda, M.
External linksMol. Immunol. / PubMed:31521018
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-6k4z:
Single-chain Fv antibody of C6 COMPLEXED WITH 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-NPA:
2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / antigen binding / affinity maturation / Somatic hypermutation / conformational change

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