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TitleEngineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 141, Page 15466-15470, Year 2019
Publish dateApr 10, 2018 (structure data deposition date)
AuthorsArora, S. / Horne, W.S. / Islam, K.
External linksJ. Am. Chem. Soc. / PubMed:31518125
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6d07:
Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6d08:
Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Lysine modification / Chromodomain / Bump-hole / Epigenetics

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