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Structure paper

TitleHuman adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Journal, issue, pagesSci Adv, Vol. 5, Page eaax3567-eaax3567, Year 2019
Publish dateJan 22, 2018 (structure data deposition date)
AuthorsBaker, A.T. / Mundy, R.M. / Davies, J.A. / Rizkallah, P.J. / Parker, A.L.
External linksSci Adv / PubMed:31517055
MethodsX-ray diffraction
Resolution1.03 - 1.19 Å
Structure data

PDB-6fjo:
Adenovirus species 26 knob protein, very high resolution
Method: X-RAY DIFFRACTION / Resolution: 1.17 Å

PDB-6qu6:
Adenovirus Serotype 26 (Ad26) in complex with sialic acid, pH4.0
Method: X-RAY DIFFRACTION / Resolution: 1.03 Å

PDB-6qu8:
Adenovirus Serotype 26 (Ad26) in complex with sialic acid, pH8.0
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

Chemicals

ChemComp-GLU:
GLUTAMIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-SLB:
N-acetyl-beta-neuraminic acid

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • human adenovirus 26
KeywordsVIRAL PROTEIN / Fiber / Fiber-knob / tropism determinant / high resolution / structure determination. adenovirus / Mastadenovirus / Adenovirus / Adenovirus 26 / Ad26 / HAdV-D26 / Ad26K / HAdV-D26K / human adenovirus / human adenovirus 26 / Sialic Acid / NANA / SIA / N-Acetylneuraminic acid / neuraminic acid / species D / adenovirus species D / AdD / HAdV-D / protein IV / pIV / head domain / knob domain / fiber protein / fibre protein / fibre-knob / knob / head

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