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TitleStructural basis for the substrate recognition of aminoglycoside 7''-phosphotransferase-Ia from Streptomyces hygroscopicus.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 75, Page 599-607, Year 2019
Publish dateDec 14, 2018 (structure data deposition date)
AuthorsTakenoya, M. / Shimamura, T. / Yamanaka, R. / Adachi, Y. / Ito, S. / Sasaki, Y. / Nakamura, A. / Yajima, S.
External linksActa Crystallogr. ,Sect. F / PubMed:31475927
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-6iy9:
Crystal structure of aminoglycoside 7"-phoshotransferase-Ia (APH(7")-Ia/HYG) from Streptomyces hygroscopicus complexed with hygromycin B
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HY0:
HYGROMYCIN B VARIANT

ChemComp-NHE:
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / pH buffer*YM

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

Source
  • streptomyces hygroscopicus (bacteria)
KeywordsTRANSFERASE / Kinase / Complex

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