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TitleCryo-EM structure of human lysosomal cobalamin exporter ABCD4.
Journal, issue, pagesCell Res, Vol. 29, Issue 12, Page 1039-1041, Year 2019
Publish dateAug 29, 2019
AuthorsDa Xu / Zhang Feng / Wen-Tao Hou / Yong-Liang Jiang / Liang Wang / Linfeng Sun / Cong-Zhao Zhou / Yuxing Chen /
External linksCell Res / PubMed:31467407 / PubMed Central
MethodsEM (single particle)
Resolution3.6 Å
Structure data

EMDB-9791, PDB-6jbj:
Cryo-EM structure of human lysosomal cobalamin exporter ABCD4
Method: EM (single particle) / Resolution: 3.6 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM / Adenosine triphosphate

Source
  • homo sapiens (human)
KeywordsABCD4 protein, human / ATP-Binding Cassette Transporters / Cryoelectron Microscopy / HEK293 Cells / Humans / Lysosomes / Protein Conformation / Vitamin B 12 / MEMBRANE PROTEIN / Human ABCD4 / Lysosomal cobalamin exporter / ATP-bound / lysosome-open conformation

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