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Structure paper

TitleCharacterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase.
Journal, issue, pagesBiochemistry, Vol. 58, Page 3918-3926, Year 2019
Publish dateMay 30, 2019 (structure data deposition date)
AuthorsMcleod, M.J. / Krismanich, A.P. / Assoud, A. / Dmitrienko, G.I. / Holyoak, T.
External linksBiochemistry / PubMed:31461616
MethodsX-ray diffraction
Resolution1.49 Å
Structure data

PDB-6p5o:
The structure of rat cytosolic PEPCK in complex with 3-(carboxymethylthiol)-picolinic acid
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-O2Y:
3-[(carboxymethyl)sulfanyl]pyridine-2-carboxylic acid

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsLYASE/INHIBITOR / kinase / gluconeogenesis / lyase / LYASE-INHIBITOR complex

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