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| Title | The 3.2 angstrom structure of a bioengineered variant of blood coagulation factor VIII indicates two conformations of the C2 domain. |
|---|---|
| Journal, issue, pages | J. Thromb. Haemost., Vol. 18, Page 57-69, Year 2020 |
| Publish date | Sep 7, 2018 (structure data deposition date) |
Authors | Smith, I.W. / d'Aquino, A.E. / Coyle, C.W. / Fedanov, A. / Parker, E.T. / Denning, G. / Spencer, H.T. / Lollar, P. / Doering, C.B. / Spiegel Jr., P.C. |
External links | J. Thromb. Haemost. / PubMed:31454152 |
| Methods | X-ray diffraction |
| Resolution | 3.19999885698 - 3.6093641312 Å |
| Structure data | ![]() PDB-6mf0: ![]() PDB-6mf2: |
| Chemicals | ![]() ChemComp-CA: ![]() ChemComp-ZN: ![]() ChemComp-CU1: ![]() ChemComp-HOH: |
| Source |
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Keywords | BLOOD CLOTTING / Hemostasis / Hemophilia A / Factor VIII / Chimera / Secreted |
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homo sapiens (human)
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