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TitleHeparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateMar 13, 2019 (structure data deposition date)
AuthorsVogtle, T. / Sharma, S. / Mori, J. / Nagy, Z. / Semeniak, D. / Scandola, C. / Geer, M.J. / Smith, C.W. / Lane, J. / Pollack, S. ...Vogtle, T. / Sharma, S. / Mori, J. / Nagy, Z. / Semeniak, D. / Scandola, C. / Geer, M.J. / Smith, C.W. / Lane, J. / Pollack, S. / Lassila, R. / Jouppila, A. / Barr, A.J. / Ogg, D.J. / Howard, T.D. / McMiken, H.J. / Warwicker, J. / Geh, C. / Rowlinson, R. / Abbott, W.M. / Eckly, A. / Schulze, H. / Wright, G.J. / Mazharian, A. / Futterer, K. / Rajesh, S. / Douglas, M.R. / Senis, Y.A.
External linksElife / PubMed:31436532
MethodsX-ray diffraction
Resolution3.13 Å
Structure data

PDB-6r0x:
The extracellular domain of G6b-B in complex with Fab fragment and DP12 heparin oligosaccharide.
Method: X-RAY DIFFRACTION / Resolution: 3.13 Å

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / platelets / signaling / ITIM-receptor / G6b-B / heparin

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