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Structure paper

TitleMolecular features of lipoprotein CD0873: A potential vaccine against the human pathogenClostridioides difficile.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 15850-15861, Year 2019
Publish dateSep 15, 2018 (structure data deposition date)
AuthorsBradshaw, W.J. / Bruxelle, J.F. / Kovacs-Simon, A. / Harmer, N.J. / Janoir, C. / Pechine, S. / Acharya, K.R. / Michell, S.L.
External linksJ. Biol. Chem. / PubMed:31420448
MethodsX-ray diffraction
Resolution1.35 - 2.5 Å
Structure data

PDB-6hni:
The ligand-bound, closed structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile.
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-6hnj:
The ligand-bound, open structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile.
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6hnk:
The ligand-free, open structure of CD0873, a substrate binding protein with adhesive properties from Clostridium difficile.
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-TYR:
TYROSINE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • peptoclostridium difficile 630 (bacteria)
KeywordsTRANSPORT PROTEIN / Substrate binding protein / adhesin / tyrosine binding protein / lipoprotein

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