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Structure paper

TitlePolymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 8899-8912, Year 2019
Publish dateDec 24, 2018 (structure data deposition date)
AuthorsSatange, R. / Chuang, C.Y. / Neidle, S. / Hou, M.H.
External linksNucleic Acids Res. / PubMed:31361900
MethodsX-ray diffraction
Resolution1.52 - 2.5 Å
Structure data

PDB-6j0h:
Crystal structure of Actinomycin D- d(TTGGCGAA) complex
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-6j0i:
Structure of [Co2+-(Chromomycin A3)2]-d(TTGGCGAA)2 complex
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CRH:
1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE

ChemComp-CO:
Unknown entry

Source
  • synthetic construct (others)
  • streptomyces sp. (bacteria)
KeywordsDNA/ANTIBIOTIC / Mismatch DNA / Actinomycin D / Drug-DNA complex / Base flip out / DNA kink / DNA-ANTIBIOTIC complex / Chromomycin A3 / G:G mismatch

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