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Structure paper

TitleMolecular mechanism of polyketide shortening in anthraquinone biosynthesis ofPhotorhabdus luminescens.
Journal, issue, pagesChem Sci, Vol. 10, Page 6341-6349, Year 2019
Publish dateOct 16, 2018 (structure data deposition date)
AuthorsZhou, Q. / Brauer, A. / Adihou, H. / Schmalhofer, M. / Saura, P. / Grammbitter, G.L.C. / Kaila, V.R.I. / Groll, M. / Bode, H.B.
External linksChem Sci / PubMed:31341589
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-6hxa:
AntI from P. luminescens catalyses terminal polyketide shortening in the biosynthesis of anthraquinones
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • photorhabdus luminescens (bacteria)
KeywordsLYASE / Natural Product Biosynthesis / Type II Polyketide Synthase System / alpha / beta-Hydrolase Fold / Cascade Reaction / Retro Claisen Reaction / Dieckmann Condensation

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