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TitleHigh-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.
Journal, issue, pagesSci Immunol, Vol. 4, Year 2019
Publish dateDec 4, 2018 (structure data deposition date)
AuthorsMoritz, A. / Anjanappa, R. / Wagner, C. / Bunk, S. / Hofmann, M. / Pszolla, G. / Saikia, A. / Garcia-Alai, M. / Meijers, R. / Rammensee, H.G. ...Moritz, A. / Anjanappa, R. / Wagner, C. / Bunk, S. / Hofmann, M. / Pszolla, G. / Saikia, A. / Garcia-Alai, M. / Meijers, R. / Rammensee, H.G. / Springer, S. / Maurer, D.
External linksSci Immunol / PubMed:31324691
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-6q3s:
Engineered Human HLA_A2 MHC Class I molecule in complex with TCR and SV9 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MHC molecule / engineered disulphide bond / TCR

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