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TitleCyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 13171-13185, Year 2019
Publish dateOct 3, 2018 (structure data deposition date)
AuthorsDujardin, M. / Madan, V. / Gandhi, N.S. / Cantrelle, F.X. / Launay, H. / Huvent, I. / Bartenschlager, R. / Lippens, G. / Hanoulle, X.
External linksJ. Biol. Chem. / PubMed:31315928
MethodsNMR (solution)
Structure data

PDB-6ht4:
NMR Structure of NS5A-D2 (JFH1) peptide (304-323)
Method: SOLUTION NMR

Source
  • hepacivirus c
KeywordsUNKNOWN FUNCTION / PW-turn

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