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Structure paper

TitleCatalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 14961-14970, Year 2019
Publish dateNov 30, 2018 (structure data deposition date)
AuthorsPravata, V.M. / Muha, V. / Gundogdu, M. / Ferenbach, A.T. / Kakade, P.S. / Vandadi, V. / Wilmes, A.C. / Borodkin, V.S. / Joss, S. / Stavridis, M.P. / van Aalten, D.M.F.
External linksProc. Natl. Acad. Sci. USA / PubMed:31296563
MethodsX-ray diffraction
Resolution2.17 Å
Structure data

PDB-6ibo:
Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

Chemicals

ChemComp-12V:
(2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE

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