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Structure paper

TitleCrystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism.
Journal, issue, pagesRes Pract Thromb Haemost, Vol. 3, Page 412-419, Year 2019
Publish dateNov 22, 2017 (structure data deposition date)
AuthorsJiang, L.G. / Xie, X. / Li, J. / Persson, E. / Huang, M.D.
External linksRes Pract Thromb Haemost / PubMed:31294329
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-5yup:
Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / FVIIa / antibodies / Fab4F5 / inhibition / coagulation / STRUCTURAL PROTEIN

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