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TitleBeyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
Journal, issue, pagesEmbo J., Vol. 38, Page e101153-e101153, Year 2019
Publish dateNov 19, 2018 (structure data deposition date)
AuthorsSheu-Gruttadauria, J. / Xiao, Y. / Gebert, L.F. / MacRae, I.J.
External linksEmbo J. / PubMed:31268608
MethodsX-ray diffraction
Resolution2.899 Å
Structure data

PDB-6n4o:
Human Argonaute2-miR-122 bound to a seed and supplementary paired target
Method: X-RAY DIFFRACTION / Resolution: 2.899 Å

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsRNA binding protein/rna / RNA-binding protein / microRNA / target directed microRNA decay / HYDROLASE-RNA complex / RNA BINDING PROTEIN / RNA binding protein-rna complex

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