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TitleStructural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 12534-12546, Year 2019
Publish dateFeb 27, 2019 (structure data deposition date)
AuthorsDeuss, F.A. / Watson, G.M. / Goodall, K.J. / Leece, I. / Chatterjee, S. / Fu, Z. / Thaysen-Andersen, M. / Andrews, D.M. / Rossjohn, J. / Berry, R.
External linksJ. Biol. Chem. / PubMed:31253644
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-6o3o:
Structure of human DNAM-1 (CD226) bound to nectin-like protein-5 (necl-5)
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / immune receptor / immunoglobulin domain / adhesion molecule

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