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Structure paper

TitleStructural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 7648-7665, Year 2019
Publish dateJul 19, 2018 (structure data deposition date)
AuthorsLiu, X. / Shen, S. / Wu, P. / Li, F. / Wang, C. / Gong, Q. / Wu, J. / Yao, X. / Zhang, H. / Shi, Y.
External linksNucleic Acids Res. / PubMed:31251801
MethodsNMR (solution) / X-ray diffraction
Resolution2.994 - 3.001 Å
Structure data

PDB-6aas:
Solution Structure for helix 45 in 3' end of 12S rRNA
Method: SOLUTION NMR

PDB-6aau:
Solution Structure for m62A helix 45 in 3' end of 12S rRNA
Method: SOLUTION NMR

PDB-6aax:
Crystal structure of TFB1M and h45 with SAM in homo sapiens
Method: X-RAY DIFFRACTION / Resolution: 2.994 Å

PDB-6ajk:
Crystal structure of TFB1M and h45 in homo sapiens
Method: X-RAY DIFFRACTION / Resolution: 3.001 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsRNA / stem-loop / h45 / TRANSFERASE/RNA / TFB1M / TRANSFERASE-RNA complex / helix45

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