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Structure paper

TitleThe role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 13958-13963, Year 2019
Publish dateJan 29, 2019 (structure data deposition date)
AuthorsZorgati, H. / Larsson, M. / Ren, W. / Sim, A.Y.L. / Gettemans, J. / Grimes, J.M. / Li, W. / Robinson, R.C.
External linksProc. Natl. Acad. Sci. USA / PubMed:31243148
MethodsX-ray diffraction
Resolution2.88 - 2.975 Å
Structure data

PDB-6jco:
Crystal structure of calcium free human gelsolin amyloid mutant D187N
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

PDB-6jeg:
Crystal structure of calcium free human gelsolin amyloid mutant G167R
Method: X-RAY DIFFRACTION / Resolution: 2.975 Å

PDB-6jeh:
Crystal structure of calcium free human gelsolin amyloid mutant D187Y
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsActin Binding Protein / gelsolin / amyloidosis / calcium activation

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