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Structure paper

TitleTwo HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d.
Journal, issue, pagesNat Commun, Vol. 10, Page 2544-2544, Year 2019
Publish dateDec 2, 2018 (structure data deposition date)
AuthorsZhang, B. / Ye, Y. / Ye, W. / Perculija, V. / Jiang, H. / Chen, Y. / Li, Y. / Chen, J. / Lin, J. / Wang, S. ...Zhang, B. / Ye, Y. / Ye, W. / Perculija, V. / Jiang, H. / Chen, Y. / Li, Y. / Chen, J. / Lin, J. / Wang, S. / Chen, Q. / Han, Y.S. / Ouyang, S.
External linksNat Commun / PubMed:31186424
MethodsX-ray diffraction
Resolution1.86 - 2.15 Å
Structure data

PDB-6iv8:
the selenomethionine(SeMet)-derived Cas13d binary complex
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-6iv9:
the Cas13d binary complex
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • uncultured ruminococcus sp (environmental samples)
  • uncultured ruminococcus sp. (environmental samples)
KeywordsRNA BINDING PROTEIN/RNA / CRISPR / Cas13d / crRNA / binary complex / RNA BINDING PROTEIN-RNA complex

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