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Title2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin.
Journal, issue, pagesFebs Lett., Vol. 593, Page 2030-2039, Year 2019
Publish dateMay 22, 2019 (structure data deposition date)
AuthorsMoseng, M.A. / Nix, J.C. / Page, R.C.
External linksFebs Lett. / PubMed:31177526
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-6p2u:
Structure of Mortalin-NBD with N6-propargyladenosine-5'-diphosphate
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NO7:
9-{5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-alpha-D-ribofuranosyl}-N-(prop-2-yn-1-yl)-9H-purin-6-amine

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCHAPERONE / inhibitor / complex / ATPase

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