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Structure paper

TitleCrystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 6973-6983, Year 2019
Publish dateOct 22, 2018 (structure data deposition date)
AuthorsJackson, L.N. / Chim, N. / Shi, C. / Chaput, J.C.
External linksNucleic Acids Res. / PubMed:31170294
MethodsX-ray diffraction
Resolution1.62 - 1.912 Å
Structure data

PDB-6mu4:
Bst DNA polymerase I FANA/DNA binary complex
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

PDB-6mu5:
Bst DNA polymerase I TNA/DNA binary complex
Method: X-RAY DIFFRACTION / Resolution: 1.912 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • geobacillus stearothermophilus (bacteria)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / XNA reverse transcription / TRANSFERASE-DNA complex

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