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TitleS-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine gamma-lyase-dependent hydrogen sulfide synthesis.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 11011-11022, Year 2019
Publish dateDec 6, 2018 (structure data deposition date)
AuthorsYadav, P.K. / Vitvitsky, V. / Kim, H. / White, A. / Cho, U.S. / Banerjee, R.
External linksJ. Biol. Chem. / PubMed:31160338
MethodsX-ray diffraction
Resolution2.495 Å
Structure data

PDB-6nba:
Crystal structure of Human Cystathionine gamma lyase with S-3-Carboxpropyl-L-Cysteine
Method: X-RAY DIFFRACTION / Resolution: 2.495 Å

Chemicals

ChemComp-P1T:
2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / complex

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