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-Structure paper
Title | Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction. |
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Journal, issue, pages | J. Biol. Chem., Vol. 294, Page 11980-11991, Year 2019 |
Publish date | Aug 23, 2018 (structure data deposition date) |
Authors | Ozeir, M. / Huyet, J. / Burgevin, M.C. / Pinson, B. / Chesney, F. / Remy, J.M. / Siddiqi, A.R. / Lupoli, R. / Pinon, G. / Saint-Marc, C. ...Ozeir, M. / Huyet, J. / Burgevin, M.C. / Pinson, B. / Chesney, F. / Remy, J.M. / Siddiqi, A.R. / Lupoli, R. / Pinon, G. / Saint-Marc, C. / Gibert, J.F. / Morales, R. / Ceballos-Picot, I. / Barouki, R. / Daignan-Fornier, B. / Olivier-Bandini, A. / Auge, F. / Nioche, P. |
External links | J. Biol. Chem. / PubMed:31160323 |
Methods | X-ray diffraction |
Resolution | 1.52 - 1.9 Å |
Structure data | PDB-6hgp: PDB-6hgq: PDB-6hgr: PDB-6hgs: |
Chemicals | ChemComp-PO4: ChemComp-HOH: ChemComp-GOL: ChemComp-MG: ChemComp-PRP: ChemComp-HPA: ChemComp-IMP: ChemComp-5GP: |
Source |
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Keywords | TRANSFERASE / Rossman fold |