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-Structure paper
Title | Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 29, Page 2410-2414, Year 2019 |
Publish date | May 9, 2019 (structure data deposition date) |
Authors | Spletstoser, J.T. / Dreabit, J. / Knox, A.N. / Benowitz, A. / Campobasso, N. / Ward, P. / Cui, G. / Lewandowski, T. / McCloskey, L. / Aubart, K.M. |
External links | Bioorg. Med. Chem. Lett. / PubMed:31160176 |
Methods | X-ray diffraction |
Resolution | 1.45 - 1.7 Å |
Structure data | PDB-6ow2: PDB-6ow7: |
Chemicals | ChemComp-NI: ChemComp-NB4: ChemComp-HOH: ChemComp-SO4: ChemComp-N9Y: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / Inhibitor / complex / metal protein / enzyme / HYDROLASE-HYDROLASE INHIBITOR complex |