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TitlePhosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateMay 7, 2019 (structure data deposition date)
AuthorsBigot, N. / Day, M. / Baldock, R.A. / Watts, F.Z. / Oliver, A.W. / Pearl, L.H.
External linksElife / PubMed:31135337
MethodsX-ray diffraction
Resolution2.81 - 3.53 Å
Structure data

PDB-6rml:
Crystal structure of TOPBP1 BRCT0,1,2 in complex with a 53BP1 phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

PDB-6rmm:
Crystal structure of TOPBP1 BRCT4,5 in complex with a 53BP1 phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 3.53 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / BRCT domain Phosphopeptide recognition

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