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-Structure paper
Title | Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs. |
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Journal, issue, pages | Febs Lett., Vol. 593, Page 1863-1873, Year 2019 |
Publish date | Mar 1, 2019 (structure data deposition date) |
![]() | Scaletti, E. / Jemth, A.S. / Helleday, T. / Stenmark, P. |
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Methods | X-ray diffraction |
Resolution | 2.28 - 2.32 Å |
Structure data | ![]() PDB-6qvg: ![]() PDB-6qvl: |
Chemicals | ![]() ChemComp-GLY: ![]() ChemComp-PEG: ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-DDF: ![]() ChemComp-PLP: ![]() ChemComp-ACT: ![]() ChemComp-HOH: ![]() ChemComp-CA: ![]() ChemComp-4DW: |
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![]() | TRANSFERASE |