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-Structure paper
Title | Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway. |
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Journal, issue, pages | J. Exp. Med., Vol. 216, Page 1525-1541, Year 2019 |
Publish date | Aug 29, 2018 (structure data deposition date) |
Authors | Fenwick, C. / Loredo-Varela, J.L. / Joo, V. / Pellaton, C. / Farina, A. / Rajah, N. / Esteves-Leuenberger, L. / Decaillon, T. / Suffiotti, M. / Noto, A. ...Fenwick, C. / Loredo-Varela, J.L. / Joo, V. / Pellaton, C. / Farina, A. / Rajah, N. / Esteves-Leuenberger, L. / Decaillon, T. / Suffiotti, M. / Noto, A. / Ohmiti, K. / Gottardo, R. / Weissenhorn, W. / Pantaleo, G. |
External links | J. Exp. Med. / PubMed:31123083 |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | PDB-6hig: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / Non-blocking antibody / PD-1/PD-L1 pathway / anti-PD-1 antibody / tumor clearance |