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TitleCrystal Structure of the Monomeric Extracellular Domain of alpha 9 Nicotinic Receptor Subunit in Complex With alpha-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to alpha 9 alpha 10 Nicotinic Receptors.
Journal, issue, pagesFront Pharmacol, Vol. 10, Page 474-474, Year 2019
Publish dateOct 19, 2018 (structure data deposition date)
AuthorsZouridakis, M. / Papakyriakou, A. / Ivanov, I.A. / Kasheverov, I.E. / Tsetlin, V. / Tzartos, S. / Giastas, P.
External linksFront Pharmacol / PubMed:31118896
MethodsX-ray diffraction
Resolution2.26 Å
Structure data

PDB-6hy7:
Crystal structure of alpha9 nAChR extracellular domain in complex with alpha-conotoxin RgIA
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • conus regius (invertebrata)
KeywordsTOXIN / alpha9 / ion channel / nAChR / acetylcholine / conotoxin / RgIA / antagonist

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