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Structure paper

TitleInfluenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope.
Journal, issue, pagesCell Host Microbe, Vol. 25, Page 827-, Year 2019
Publish dateNov 21, 2018 (structure data deposition date)
AuthorsBajic, G. / Maron, M.J. / Adachi, Y. / Onodera, T. / McCarthy, K.R. / McGee, C.E. / Sempowski, G.D. / Takahashi, Y. / Kelsoe, G. / Kuraoka, M. / Schmidt, A.G.
External linksCell Host Microbe / PubMed:31104946
MethodsX-ray diffraction
Resolution3 - 3.5 Å
Structure data

PDB-6n5b:
Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-6n5d:
Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6n5e:
Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NGA:
2-acetamido-2-deoxy-beta-D-galactopyranose

Source
  • mus musculus (house mouse)
  • influenza a virus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / influenza / antibody / complex / hemagglutinin / immunogen design / glycan / VIRAL PROTEIN-IMMUNE SYSTEM complex

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