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Structure paper

TitleSARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation.
Journal, issue, pagesJ. Mol. Biol., Vol. 431, Page 2869-2883, Year 2019
Publish dateFeb 24, 2019 (structure data deposition date)
AuthorsKimberlin, C.R. / Meshcheriakova, A. / Palty, R. / Raveh, A. / Karbat, I. / Reuveny, E. / Minor Jr., D.L.
External linksJ. Mol. Biol. / PubMed:31082439
MethodsX-ray diffraction
Resolution1.58 - 2.101 Å
Structure data

PDB-6o2u:
Crystal structure of the SARAF luminal domain
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6o2v:
Crystal structure of the SARAF luminal domain Cys-lock mutant monomer
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

PDB-6o2w:
Crystal structure of the SARAF luminal domain Cys-lock mutant dimer
Method: X-RAY DIFFRACTION / Resolution: 2.101 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FMT:
FORMIC ACID

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / SOCE / Store Operated Calcium Entry / SARAF / ER / Endoplasmic reticulum / Calcium signaling / Domain swap

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