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TitleSelecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.
Journal, issue, pagesCell Death Differ., Vol. 27, Page 117-129, Year 2020
Publish dateApr 29, 2018 (structure data deposition date)
AuthorsGozzi, G.J. / Gonzalez, D. / Boudesco, C. / Dias, A.M.M. / Gotthard, G. / Uyanik, B. / Dondaine, L. / Marcion, G. / Hermetet, F. / Denis, C. ...Gozzi, G.J. / Gonzalez, D. / Boudesco, C. / Dias, A.M.M. / Gotthard, G. / Uyanik, B. / Dondaine, L. / Marcion, G. / Hermetet, F. / Denis, C. / Hardy, L. / Suzanne, P. / Douhard, R. / Jego, G. / Dubrez, L. / Demidov, O.N. / Neiers, F. / Briand, L. / Sopkova-de Oliveira Santos, J. / Voisin-Chiret, A.S. / Garrido, C.
External linksCell Death Differ. / PubMed:31068676
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-6gfa:
Structure of Nucleotide binding domain of HSP110, ATP and Mg2+ complexed
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCHAPERONE / HSP110 / HSP110DE9 / Nucleotide-binding domain / HSPH1 / HSP105

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