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TitleCrystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 667, Page 6-13, Year 2019
Publish dateOct 3, 2018 (structure data deposition date)
AuthorsJaruwat, A. / Riangrungroj, P. / Ubonprasert, S. / Sae-Ueng, U. / Kuaprasert, B. / Yuthavong, Y. / Leartsakulpanich, U. / Chitnumsub, P.
External linksArch. Biochem. Biophys. / PubMed:31002765
MethodsX-ray diffraction
Resolution2.48 Å
Structure data

PDB-6ii7:
Crystal structure of Plasmodium falciparum adenosine deaminase C27Q+L227I mutant co-complexed with Zn ion, hypoxanthine and inosine
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

Chemicals

ChemComp-NOS:
INOSINE

ChemComp-HPA:
HYPOXANTHINE

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum 3d7 (eukaryote)
KeywordsHYDROLASE / TIM barrel

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