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Structure paper

TitleCross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk.
Journal, issue, pagesNat Commun, Vol. 10, Page 1788-1788, Year 2019
Publish dateNov 27, 2018 (structure data deposition date)
AuthorsKing, L.B. / West, B.R. / Moyer, C.L. / Gilchuk, P. / Flyak, A. / Ilinykh, P.A. / Bombardi, R. / Hui, S. / Huang, K. / Bukreyev, A. ...King, L.B. / West, B.R. / Moyer, C.L. / Gilchuk, P. / Flyak, A. / Ilinykh, P.A. / Bombardi, R. / Hui, S. / Huang, K. / Bukreyev, A. / Crowe Jr., J.E. / Saphire, E.O.
External linksNat Commun / PubMed:30996276
MethodsX-ray diffraction
Resolution2.03 - 3.684 Å
Structure data

PDB-6n7j:
BDBV223 Fab bound to synthetic peptide of Bundibugyo virus Glycoprotein Stalk
Method: X-RAY DIFFRACTION / Resolution: 3.684 Å

PDB-6n7u:
apo-BDBV223 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • bundibugyo ebolavirus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / antibody / antiviral protein / VIRAL PROTEIN-IMMUNE SYSTEM complex / IMMUNE SYSTEM / Fab

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