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Title | High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-beta-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. |
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Journal, issue, pages | Molecules, Vol. 24, Year 2019 |
Publish date | Mar 13, 2019 (structure data deposition date) |
![]() | Fischer, T. / Koulas, S.M. / Tsagkarakou, A.S. / Kyriakis, E. / Stravodimos, G.A. / Skamnaki, V.T. / Liggri, P.G.V. / Zographos, S.E. / Riedl, R. / Leonidas, D.D. |
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Methods | X-ray diffraction |
Resolution | 2.4 - 2.5 Å |
Structure data | ![]() PDB-6r0h: ![]() PDB-6r0i: |
Chemicals | ![]() ChemComp-JN2: ![]() ChemComp-PLP: ![]() ChemComp-HOH: ![]() ChemComp-JNB: |
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![]() | TRANSFERASE |