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Structure paper

TitleStructural basis for mammalian nucleotide sugar transport.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateApr 4, 2019 (structure data deposition date)
AuthorsAhuja, S. / Whorton, M.R.
External linksElife / PubMed:30985278
MethodsX-ray diffraction
Resolution2.58 - 3.38 Å
Structure data

PDB-6oh2:
X-ray crystal structure of the mouse CMP-sialic acid transporter in complex with CMP, by lipidic cubic phase
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

PDB-6oh3:
X-ray crystal structure of the mouse CMP-sialic acid transporter in complex with CMP-sialic acid, by lipidic cubic phase
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-6oh4:
X-ray crystal structure of the mouse CMP-sialic acid transporter in complex with CMP, by hanging drop vapor diffusion
Method: X-RAY DIFFRACTION / Resolution: 3.38 Å

Chemicals

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-NCC:
CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID

Source
  • mus musculus (house mouse)
KeywordsTRANSPORT PROTEIN / drug/metabolite transporter / nucleotide-sugar / sialic acid / glycosylation

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