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Structure paper

TitleA unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 5405-5419, Year 2019
Publish dateMar 24, 2018 (structure data deposition date)
AuthorsWu, C.C. / Lin, J.L.J. / Yang-Yen, H.F. / Yuan, H.S.
External linksNucleic Acids Res. / PubMed:30949702
MethodsX-ray diffraction
Resolution2.321 - 2.986 Å
Structure data

PDB-5zki:
Human EXOG-H140A in complex with duplex DNA
Method: X-RAY DIFFRACTION / Resolution: 2.321 Å

PDB-5zkj:
Human EXOG-H140A in complex with RNA/DNA hybrid duplex
Method: X-RAY DIFFRACTION / Resolution: 2.798 Å

PDB-6iid:
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
Method: X-RAY DIFFRACTION / Resolution: 2.986 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / Enzyme-substrate complex / Mitochondrial exonuclease / HYDROLASE-DNA complex / HYDROLASE/RNA/DNA / HYDROLASE-RNA-DNA complex / DNA BINDING PROTEIN

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