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Structure paper

TitleNeutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Journal, issue, pagesNat Microbiol, Vol. 4, Page 1231-1241, Year 2019
Publish dateSep 13, 2018 (structure data deposition date)
AuthorsWang, Q. / Ma, T. / Wu, Y. / Chen, Z. / Zeng, H. / Tong, Z. / Gao, F. / Qi, J. / Zhao, Z. / Chai, Y. ...Wang, Q. / Ma, T. / Wu, Y. / Chen, Z. / Zeng, H. / Tong, Z. / Gao, F. / Qi, J. / Zhao, Z. / Chai, Y. / Yang, H. / Wong, G. / Bi, Y. / Wu, L. / Shi, R. / Yang, M. / Song, J. / Jiang, H. / An, Z. / Wang, J. / Yilma, T.D. / Shi, Y. / Liu, W.J. / Liang, M. / Qin, C. / Gao, G.F. / Yan, J.
External linksNat Microbiol / PubMed:30936489
MethodsX-ray diffraction
Resolution2 - 3.2 Å
Structure data

PDB-6iea:
Structure of RVFV Gn and human monoclonal antibody R13
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6ieb:
Structure of RVFV Gn and human monoclonal antibody R15
Method: X-RAY DIFFRACTION / Resolution: 2.409 Å

PDB-6iec:
Structure of RVFV Gn and human monoclonal antibody R17
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-6iek:
Structure of RVFV Gn and human monoclonal antibody R12
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • rift valley fever virus
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN/IMMUNE SYSTEM / RVFV / antibody / STRUCTURAL PROTEIN / STRUCTURAL PROTEIN-IMMUNE SYSTEM complex

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