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Structure paper

TitleStructural and functional properties of Grb2 SH2 dimer in CD28 binding.
Journal, issue, pagesBiophys Physicobio., Vol. 16, Page 80-88, Year 2019
Publish dateSep 6, 2018 (structure data deposition date)
AuthorsHosoe, Y. / Numoto, N. / Inaba, S. / Ogawa, S. / Morii, H. / Abe, R. / Ito, N. / Oda, M.
External linksBiophys Physicobio. / PubMed:30923665
MethodsX-ray diffraction
Resolution1.15 - 2 Å
Structure data

PDB-6icg:
Grb2 SH2 domain in phosphopeptide free form
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

PDB-6ich:
Grb2 SH2 domain in domain swapped dimer form
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Src homology 2 domain / phosphorylated tyrosine / Adapter protein

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