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Structure paper

TitleZooming in on protons: Neutron structure of protein kinase A trapped in a product complex.
Journal, issue, pagesSci Adv, Vol. 5, Page eaav0482-eaav0482, Year 2019
Publish dateJul 10, 2018 (structure data deposition date)
AuthorsGerlits, O. / Weiss, K.L. / Blakeley, M.P. / Veglia, G. / Taylor, S.S. / Kovalevsky, A.
External linksSci Adv / PubMed:30906862
MethodsX-ray diffraction / neutron diffraction
Resolution2 Å
Structure data

PDB-6e21:
Joint X-ray/neutron structure of PKAc with products Sr2-ADP and phosphorylated peptide SP20
Method: X-RAY DIFFRACTION / NEUTRON DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SR:
STRONTIUM ION

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-DOD:
DEUTERATED WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsTRANSFERASE / protein kinase / phosphorylated product complex

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