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TitleStructural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor.
Journal, issue, pagesStructure, Vol. 27, Page 741-, Year 2019
Publish dateAug 27, 2018 (structure data deposition date)
AuthorsKukimoto-Niino, M. / Tsuda, K. / Ihara, K. / Mishima-Tsumagari, C. / Honda, K. / Ohsawa, N. / Shirouzu, M.
External linksStructure / PubMed:30853411
MethodsX-ray diffraction
Resolution3.23 - 3.256 Å
Structure data

PDB-6aj4:
Crystal structure of the DHR-2 domain of DOCK7 in complex with Cdc42
Method: X-RAY DIFFRACTION / Resolution: 3.256 Å

PDB-6ajl:
DOCK7 mutant I1836Y complexed with Cdc42
Method: X-RAY DIFFRACTION / Resolution: 3.23 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / DOCK / GEF / DHR-2 / GTPase / Rho / Rac / Cdc42 / mutant

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