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Structure paper

TitleCardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2.
Journal, issue, pagesJCI Insight, Vol. 5, Year 2019
Publish dateMay 12, 2017 (structure data deposition date)
AuthorsAlvarado, F.J. / Bos, J.M. / Yuchi, Z. / Valdivia, C.R. / Hernandez, J.J. / Zhao, Y.T. / Henderlong, D.S. / Chen, Y. / Booher, T.R. / Marcou, C.A. ...Alvarado, F.J. / Bos, J.M. / Yuchi, Z. / Valdivia, C.R. / Hernandez, J.J. / Zhao, Y.T. / Henderlong, D.S. / Chen, Y. / Booher, T.R. / Marcou, C.A. / Van Petegem, F. / Ackerman, M.J. / Valdivia, H.H.
External linksJCI Insight / PubMed:30835254
MethodsX-ray diffraction
Resolution1.439 Å
Structure data

PDB-5vsn:
Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L
Method: X-RAY DIFFRACTION / Resolution: 1.439 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSPORT PROTEIN / Ryanodine Receptor / Disease Mutant

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