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Structure paper

TitleOligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
Journal, issue, pagesACS Cent Sci, Vol. 5, Page 237-249, Year 2019
Publish dateApr 3, 2018 (structure data deposition date)
AuthorsNguyen, D.N. / Xu, B. / Stanfield, R.L. / Bailey, J.K. / Horiya, S. / Temme, J.S. / Leon, D.R. / LaBranche, C.C. / Montefiori, D.C. / Costello, C.E. ...Nguyen, D.N. / Xu, B. / Stanfield, R.L. / Bailey, J.K. / Horiya, S. / Temme, J.S. / Leon, D.R. / LaBranche, C.C. / Montefiori, D.C. / Costello, C.E. / Wilson, I.A. / Krauss, I.J.
External linksACS Cent Sci / PubMed:30834312
MethodsX-ray diffraction
Resolution2.298 - 3.586 Å
Structure data

PDB-6cxg:
anti-HIV-1 Fab 2G12 in complex with glycopeptide 10V1S
Method: X-RAY DIFFRACTION / Resolution: 2.298 Å

PDB-6cxl:
anti-HIV-1 Fab 2G12 in complex with glycopeptide 10F5
Method: X-RAY DIFFRACTION / Resolution: 3.586 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / antibody / glycopeptide / HIV-1 / glycobiology

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