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-Structure paper
Title | Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of beta-glucocerebrosidase inhibition. |
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Journal, issue, pages | Bioorg. Chem., Vol. 86, Page 652-664, Year 2019 |
Publish date | Oct 5, 2018 (structure data deposition date) |
Authors | Martinez-Bailen, M. / Carmona, A.T. / Patterson-Orazem, A.C. / Lieberman, R.L. / Ide, D. / Kubo, M. / Kato, A. / Robina, I. / Moreno-Vargas, A.J. |
External links | Bioorg. Chem. / PubMed:30825709 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-6moz: |
Chemicals | ChemComp-NAG: ChemComp-NA: ChemComp-JXA: ChemComp-PO4: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / TIM-BARREL / GLYCOSIDASE / CEREZYME / HYDROLYSIS / INHIBITOR COMPLEX / PHARMACOLOGICAL CHAPERONE |