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Structure paper

TitleStructural characterization of the alpha-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B.
Journal, issue, pagesJ. Struct. Biol., Vol. 205, Page 65-71, Year 2019
Publish dateJan 28, 2015 (structure data deposition date)
AuthorsBirrane, G. / Dassier, A.L. / Romashko, A. / Lundberg, D. / Holmes, K. / Cottle, T. / Norton, A.W. / Zhang, B. / Concino, M.F. / Meiyappan, M.
External linksJ. Struct. Biol. / PubMed:30802506
MethodsX-ray diffraction
Resolution2.32 Å
Structure data

PDB-4xwh:
Crystal structure of the human N-acetyl-alpha-glucosaminidase
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-XYL:
Xylitol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Glycosidase

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