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TitleStructural and functional characterization of the membrane-permeabilizing activity ofNicotiana occidentalisdefensin NoD173 and protein engineering to enhance oncolysis.
Journal, issue, pagesFaseb J., Vol. 33, Page 6470-6482, Year 2019
Publish dateOct 15, 2018 (structure data deposition date)
AuthorsLay, F.T. / Ryan, G.F. / Caria, S. / Phan, T.K. / Veneer, P.K. / White, J.A. / Kvansakul, M. / Hulett, M.D.
External linksFaseb J. / PubMed:30794440
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-6mry:
NoD173 plant defensin
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-I3C:
5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • nicotiana occidentalis (plant)
KeywordsANTITUMOR PROTEIN / Defensin / Plant / Cancer

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