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Structure paper

TitleStructural insights into SETD3-mediated histidine methylation on beta-actin.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateSep 7, 2018 (structure data deposition date)
AuthorsGuo, Q. / Liao, S. / Kwiatkowski, S. / Tomaka, W. / Yu, H. / Wu, G. / Tu, X. / Min, J. / Drozak, J. / Xu, C.
External linksElife / PubMed:30785395
MethodsX-ray diffraction
Resolution1.952 - 2.15 Å
Structure data

PDB-6ict:
Structure of SETD3 bound to SAH and methylated actin
Method: X-RAY DIFFRACTION / Resolution: 1.952 Å

PDB-6icv:
Structure of SETD3 bound to SAH and unmodified actin
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / histidine methylatransferase / Structural Genomics / Structural Genomics Consortium / SGC

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